Figure 6.
Survival following LPS administration in IL-10−/− mice. Animals were treated with LPS, either 0.25, 2.5 or 10 μg per animal, as described in Methods. Animals were treated with IaIp (IaIp + LPS 0.25 (blue, n=8); IaIp + LPS 2.5 (green, n=5); IaIp + LPS 10 (red, n=10)) or HSA (HSA + LPS 0.25 (blue-dotted, n=8); HSA + LPS 2.5 (green-dotted, n=5); HSA + LPS 10 (red-dotted, n=10)) as described in Methods 1 hour following LPS. Animals were examined every 4 hours for survival. All IaIp treated animals had significantly better survival than each of their respective control groups, p = 0.006.