Table 1.
Demographic and clinical characteristics of patients with regard to adjuvant chemotherapy following liver metastasectomy
| Characteristic | Adjuvant chemotherapy | Total no. | P a | |
|---|---|---|---|---|
| FU/LV no. (%) | FOLFOX/FOLFIRI no. (%) | |||
| Total | 19 (38) | 31 (62) | 50 (100) | |
| Age (years) | ||||
| ≤70 | 6 (12) | 20 (40) | 26 (52) | 0.04 |
| >70 | 13 (26) | 11 (22) | 24 (48) | |
| Gender | ||||
| Male | 13 (26) | 21 (42) | 34 (68) | 1.0 |
| Female | 6 (12) | 10 (20) | 16 (32) | |
| Primary tumor | ||||
| Colon | 10 (20) | 24 (48) | 33 (66) | 0.12 |
| Rectum | 9 (18) | 7 (14) | 16(32) | |
| Stage of primary CRC | ||||
| II | 8 (16) | 11 (22) | 19(38) | 0.77 |
| III | 11 (22) | 20 (40) | 31 (62) | |
| Maximum CLM size | ||||
| ≤3 cm | 9 (18) | 21 (42) | 30 (60) | 0.24 |
| >3 cm | 10 (20) | 10 (20) | 20 (40) | |
| Number of CLMs | ||||
| 1 | 10 (20) | 19 (38) | 29 (58) | 0.57 |
| ≥2 | 9 (18) | 12 (24) | 21 (42) | |
| CLM distribution | ||||
| Unilobar | 13 (26) | 27 (54) | 40 (80) | 0.15 |
| Bilobar | 6 (12) | 4 (8) | 10 (20) | |
| Time from surgery of primary CRC to metastasis (months) | ||||
| ≤12 | 12 (24) | 12 (24) | 24 (48) | 0.15 |
| >12 | 7 (14) | 19 (36.7) | 26 (52) | |
| CEA at metastasectomy (ng/ml) | ||||
| ≤50 | 14 (28) | 25 (50) | 39 (78) | 0.73 |
| >50 | 5 (10) | 6 (12) | 11 (22) | |
| CLM resection margin | ||||
| R0 resection | 18 (36) | 28 (56) | 46 (92) | 0.66 |
| R1 resection | 1 (2.0) | 3 (6.0) | 4 (8.0) | |
| Prior FOLFOX/FOLFIRI following resection of primary CRC | ||||
| Yes | 0 (0) | 4 (8) | 4 (8) | 0.15 |
| No | 19 (38) | 27 (54) | 46 (92) | |
a P values were calculated with the use of Pearson’s chi-square test