Table 2. Baseline histologic characteristics by portal inflammation status, adults only (N=728).

	Portal Inflammation			P-value*
	None (N=117)	Mild (N=440)	More than mild (N=171)	None vs. mild	None vs. more than mild
Steatosis amount				0.66	0.01
<5%	5 (4.3%)	24 (5.5%)	13 (7.6%)
5-33%	43 (36.8%)	160 (36.4%)	91 (53.2%)
34-66%	42 (35.9%)	135 (30.7%)	40 (23.4%)
>66%	27 (23.1%)	121 (27.5%)	27 (15.8%)
Steatosis location				0.003	<0.0001
Zone 3 (Central)	67 (57.3%)	169 (38.6%)	28 (16.4%)
Zone 1 (Periportal)	0 (0%)	4 (0.9%)	4 (2.3%)
Azonal	23 (19.7%)	103 (23.5%)	89 (52.1%)
Panacinar	27 (23.1%)	162 (37.0%)	50 (29.2%)
Lobular inflammation score				0.47	0.28
0	2 (1.7%)	2 (0.5%)	0 (0%)
<2 under 20x mag	57 (48.7%)	220 (50.0%)	75 (43.9%)
2-4 under 20x mag	44 (37.6%)	171 (38.9%)	69 (40.4%)
>4 under 20x mag	14 (12.0%)	47 (10.7%)	27 (15.8)
Ballooning				<0.0001	<0.0001
None	58 (49.6%)	147 (33.4%)	26 (15.2%)
Few	36 (30.8%)	121 (27.5%)	43 (25.2%)
Many	23 (19.7%)	172 (39.1%)	102 (59.7%)
Fibrosis score				<0.0001	<0.0001
None	47 (40.2%)	109 (25.2%)	10 (6.0%)
Mild, zone 3 perisinusoidal	32 (27.4%)	73 (16.9%)	6 (3.6%)
Moderate, zone 3, perisinusoidal	21 (18.0%)	44 (10.2%)	5 (3.0%)
Portal/periportal only	2 (1.7%)	22 (5.1%)	6 (3.6%)
Zone 3 and periportal, any combination	10 (8.6%)	87 (20.1%)	38 (22.6%)
Bridging	4 (3.4%)	73 (16.9%)	60 (35.7%)
Cirrhosis	1 (0.9%)	24 (5.6%)	43 (25.6%)
Biopsy Diagnosis				0.002	<0.0001
Definitely not Steatohepatitis	41 (35.0%)	93 (21.2%)	20 (11.7%)
Suspicious/borderline/indeterminate: Zone 3 pattern	29 (24.8%)	89 (20.3%)	22 (12.9%)
Suspicious/borderline/indeterminate: Zone 1, periportal pattern	0 (0%)	3 (0.7%)	5 (2.9%)
Definite Steatohepatitis	47 (40.2%)	254 (57.9%)	124 (72.5%)

Note: Values are N=s (%)

^*P-values calculated using Fisher=s Exact test