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Biological effects of remote ischemic preconditioning. Transient ischemia of the arm or leg liberates a circulating effector that induces remote cellular adaptation to a subsequent, extended, and potentially lethal period of ischemia in remote tissues. Reproduced with permission from reference 57: Kharbanda RK, Nielsen TT, Redington AN. Translation of remote ischaemic preconditioning into clinical practice. Lancet. 2009;374:1557–65.
