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. 2010 Jun 2;299(2):F412–F417. doi: 10.1152/ajprenal.00211.2010

Fig. 5.

Fig. 5.

Effects of adenosine receptor antagonists on maximal TGF responses in response to an increase in perfusion of loop of Henle from 0 to 40 nl/min. The A2A receptor antagonist (ZM-241385; 10−7 mol/l) enhanced the TGF response compared with control (ATF alone). The A1 receptor antagonist (PSB-36; 10−8 mol/l) was associated with a significant inverse TGF response (P < 0.05). Simultaneous treatment with A1 (PSB-36; 10−8 mol/l) and A2A (ZM-241385; 10−7 mol/l) receptor antagonists abolished the TGF response. Values are means ± SE. *P < 0.05.