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. 2010 May 27;299(2):G440–G448. doi: 10.1152/ajpgi.00098.2010

Fig. 1.

Fig. 1.

Effect of consumption of a high-fat (HF) diet on body weight, adiposity, and food intake in low-fat (LF) and HF-fed animals after 8 or 12 wk on respective diets A: there was a significant increase in body weight in diet-induced obesity-prone (DIO-P) rats compared with diet-induced obesity-resistant (DIO-R) or LF animals (DIO-P vs. LF, P < 0.001, DIO-P vs. DIO-R, P < 0.01). B: adiposity index was calculated as the sum of the fat pads expressed as a percentage of total body weight. After 8 or 12 wk on the diets, DIO-P rats showed a significantly higher adiposity than LF and DIO-R rats (DIO-P vs. LF or DIO-R, P < 0.01 at 8 wk, P < 0.001 at 12 wk). There was a significant increase in adiposity after 12 wk compared with 8 wk (*P < 0.05) in DIO-P rats. C: starting at week 4, the DIO-P group had a significantly higher energy intake than LF and DIO-R animals (week 4: DIO-P vs. LF, P < 0.001, DIO-P vs. DIO-R, P < 0.01; week 7: DIO-P vs. LF or DIO-R, P < 0.05; week 10: DIO-P vs. LF or DIO-R, P < 0.001). Data are means ± SE; n, no. of rats. Different letters denote significant differences between groups.