Figure 4.
Amino acid sequences of the BH3 domains. The sequences of various BH3-only and BH3-only-like proteins, their accession numbers and amino acid coordinates are indicated. The consensus sequence of BH3 domain is shown in the bottom, Φ represents a hydrophobic residue (Φ2 is usually leucine); Σ is a small residue (G, A, S), Ζ is usually an acidic residue; and Γ is a hydrophilic residue (N, H, D or Y) (Day et al., 2008).