Table 2.

Phenylalanine blood concentrations and kinetics across the leg

			2 h Post-Ex
	Baseline	1 h Post-Ex	EAA + LCHO	EAA + HCHO
Blood flow, ml·min−1·100 ml leg−1	3.4 ± 0.5	5.3 ± 0.8	4.0 ± 0.8	4.0 ± 0.7
Arterial Phe, μmol/l	55 ± 2	54 ± 2	146 ± 13*	160 ± 4*
Intracellular Phe, μmol/l	93 ± 17	78 ± 11	185 ± 9*	142 ± 13*
NB, net balance across the leg	−12 ± 3	−14 ± 5	107 ± 55*	100 ± 19*
Fin, delivery to the leg	189 ± 28	289 ± 47	561 ± 122*	646 ± 118*
Fout, release from the leg	201 ± 29	304 ± 49	454 ± 113*	547 ± 108*
Rd, rate of disappearance (synthesis)	64 ± 13	65 ± 11	157 ± 61*	154 ± 28*
FM,O, release from proteolysis	88 ± 17	83 ± 12	51 ± 12†	55 ± 16‡
FO,M, utilization for protein synthesis	76 ± 16	68 ± 12	158 ± 61*	154 ± 30*

Data for baseline are pooled from both groups and are an hourly average of basal blood draws in the absence of nutrients and prior to performing exercise. Data for 1 h post-Ex are pooled and are an hourly average of blood draws in the absence of nutrients and during the 1st hour following exercise. EAA+LCHO and EAA+HCHO values are an hourly average of blood draws during the 2nd hour postexercise and 1 h following ingestion of either the EAA+LCHO or EAA+HCHO nutrient solution, respectively. Values for NB, F_in, F_out, R_d, F_M,O, and F_O,M, are expressed in nmol·min⁻¹·(100 ml leg volume)⁻¹. Phe, phenylalanine. All data are means ± SE

^*Significantly different from baseline (P < 0.05);

^†P = 0.15,

^‡P = 0.12. Blood flow, Phe concentrations, and NB data for EAA+LCHO are from a subset of a group of subjects that has been previously published (14). All other kinetic measures have not been previously published.