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. 2010 Jun 10;299(2):R480–R485. doi: 10.1152/ajpregu.00256.2010

Fig. 3.

Fig. 3.

Pretreatment phosphorylation of p38 MAPK in CSF prior to PTI (0 min) and as a function of time (hour) after PTI in vehicle, or pretreated with rtPA (2 mg/kg iv), PAI-1-DP, U0126, SB203580, SP600125, or D-JNKI1 (ERK, p38, and JNK MAPK inhibitors, all 1 mg/kg iv), n = 5 per group. Data expressed as %control by ELISA determination of phospho-MAPK and total MAPK isoforms and subsequent normalization to total form. Pretreatment was 30 min before PTI. *P < 0.05 vs. corresponding time 0 value; +P < 0.05 vs. corresponding PTI nontreated value.