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. 2010 Apr 21;299(2):C240–C250. doi: 10.1152/ajpcell.00438.2009

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Fig. 1. — Pyruvate upregulates electron transport chain enzymes but decreases metabolic rate. A and B: mRNA expression levels of cytochrome c (CytC) (A) and cytochrome-c oxidase subunit I (COX I) (B) relative to GAPDH. AU, arbitrary units. C and D: protein content of succinate dehydrogenase (SDH) (C) and COX IV (D) relative to total eukaryotic elongation factor 2 (teEF2) content. E: oxygen consumption rate (OCR) following 72-h pyruvate or NaCl treatment. *Significantly different from NaCl (P < 0.05).

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