Apo-TraR accumulation and stability in protease-deficient
strains. (A) TraR accumulation assayed with the use of
Western immunoblots. Lanes 1 and 2, wild type; lanes 3 and 4,
hflB; lanes 5 and 6, hslVU ; lanes 7 and
8, clpP; lanes 9 and 10, lon; lanes 11
and 12, clp, lon; lanes 13 and 14, clp, lon,
hslVU. Samples in odd- and even-numbered lanes are from cells
cultured in the absence and presence of AAI, respectively.
(B) Pulse-labeled TraR in wild-type and
protease-deficient E. coli strains. The upper bands are
probably due to translation of a particularly stable mRNA from
chromosome or a gene containing a T7-like promoter. (C)
TraR turnover rates obtained from the data in B.
Calculated half-lives are indicated in parentheses. (D)
Stabilization of TraR by AAI in wild-type strain and in a clp,
lon mutant. (E) TraR turnover rates calculated
from data in D.