Table 3.
SNP | Rank | P | qa | Replication Pb | Chromosome | Position, base pair | Type | Ancestral allele | Closest gene |
---|---|---|---|---|---|---|---|---|---|
rs6984368 | 1 | 8.76 × 10−6 | .6834 | .158 | 8 | 82055464 | Intronic | G | PAG1 |
rs7006101 | 22 | 4.81 × 10−5 | .7105 | 6.58 × 10−2 | 8 | 82059755 | Synonymous | C | PAG1 |
rs16899646 | 2 | 1.33 × 10−5 | .6834 | .114 | 6 | 31524899 | Intergenic | C | HCP5 |
rs1691946 | 3 | 1.70 × 10−5 | .6834 | .995 | 10 | 29200463 | Intronic | G | C10orf126 |
rs1775929 | 7 | 2.69 × 10−5 | .6834 | .881 | 10 | 29199354 | Intronic | T | C10orf126 |
rs1691943 | 8 | 2.69 × 10−5 | .6834 | .881 | 10 | 29200842 | Intronic | G | C10orf126 |
rs1775933 | 11 | 3.10 × 10−5 | .6834 | .844 | 10 | 29200882 | Intronic | G | C10orf126 |
rs11648686 | 4 | 1.78 × 10−5 | .6834 | .175 | 16 | 50950897 | Intergenic | G | TOX3 |
rs4800820 | 5 | 2.20 × 10−5 | .6834 | .710 | 18 | 23630471 | Intergenic | T | CDH2 |
rs9957708 | 9 | 2.71 × 10−5 | .6834 | .523 | 18 | 23633388 | Intergenic | A | CDH2 |
rs7102407 | 6 | 2.32 × 10−5 | .6834 | .828 | 11 | 9512693 | Intergenic | C | ZNF143 |
rs10082685 | 38 | 7.89 × 10−5 | .7185 | .460 | 11 | 9500492 | Intronic | G | ZNF143 |
rs4910466 | 39 | 8.28 × 10−5 | .7263 | 4.79 × 10−2 | 11 | 9465928 | Intronic | G | ZNF143 |
rs12332694 | 10 | 2.71 × 10−5 | .6834 | .942 | 5 | 79377745 | Intronic | C | THBS4 |
rs775095 | 12 | 3.20 × 10−5 | .6834 | .346 | 20 | 15917077 | Intronic | T | MACROD2 |
rs4910052 | 13 | 3.31 × 10−5 | .6834 | 1.50 × 10−2 | 11 | 9411950 | Synonymous | T | IPO7 |
rs36048375 | 14 | 3.31 × 10−5 | .6834 | 1.49 × 10−2 | 11 | 9419893 | Intronic | G | IPO7 |
rs7983751 | 15 | 3.37 × 10−5 | .6834 | .673 | 13 | 29992021 | Intronic | T | HMGB1 |
rs11622505 | 16 | 3.46 × 10−5 | .6834 | .980 | 14 | 92387319 | Intergenic | A | GOLGA5 |
rs17762150 | 17 | 3.64 × 10−5 | .6834 | 8.30 × 10−4 | 1 | 212191441 | Intergenic | C | PROX1 |
rs1367951 | 30 | 6.69 × 10−5 | .7105 | 5.90 × 10−4 | 1 | 212192136 | Intergenic | A | PROX1 |
rs17762192 | 34 | 7.13 × 10−5 | .7105 | 4.80 × 10−4 | 1 | 212191750 | Intergenic | G | PROX1 |
rs2267420 | 18 | 3.73 × 10−5 | .6834 | .220 | 22 | 38678466 | Intronic | A | GRAP2 |
rs498280 | 19 | 3.84 × 10−5 | .6834 | 7.88 × 10−2 | 7 | 105188251 | 3′_utr | C | ATXN7L1 |
rs17050206 | 20 | 3.95 × 10−5 | .6834 | .700 | 4 | 139372068 | Intronic | C | SLC7A11 |
NOTE. Boldface type SNPs in adjacent rows represent linked SNPs (r2 > 0.09).
P values corrected for false discovery rate (q values).
P values for AIDS 1987 diagnoses in the replication cohort, uncorrected for multiple tests.