Table 1.

The effect of MB treatment on factors of the coagulation system

Parameter	Reference range	FFP before treatment (n = 18)		MB plasma (n = 18)		Percent decrease or increase
		mean ± SD	range	mean ± SD	range	mean	range
TT, s	16-21	21.3 ± 0.9	19.7–22.9	23.8 ± 0.9∗	22.3–25.1	+11.5	4.4–20.1
RT, s	16-22	18.5 ± 1.9	15.5–21.7	20.9 ± 2.4	17.0–24.5	+12.7	−11.1–48.8
Fibrinogen (Clauss), g/l	1.8–4.5	2.4 ± 0.2	1.8–3.0	2.2 ± 0.2∗	1.7–2.8)	−6.9	−13.0–0.0
Fibrinogen (Ag), g/l	1.82–3.52	2.80 ± 0.6	1.60–4.23	2.83 ± 0.6	1.60–4.23	+1.0	−4.9–15.9
FV, %	60-140	123.6 ± 23.6	88-164	112.8 ± 21.3∗	81-145	−8.8	−13.5 to −6.2
FVIII, %	50-140	87.0 ± 23.0	48-146	76.8 ± 24.1∗	45-136	−11.7	−28.6–4.9
FXI, %	65-150	117.8 ± 19.0	85-150	97.2 ± 17.8∗	71-135	−17.5	−24.1 to −10.0
Protein S, %	67-132	85.7 ± 13.1	60-116	80.9 ± 13.0∗	56-108.5	−5.6	−10.6 to −1.0

^∗p ≤0.001 compared to untreated FFP (paired t-test).