Figure 5.

Improved concordance of measurement of samples from the TEDDY study. Results are shown for children samples that were found to be discordant for IA-2A (upper panels, n = 24) and GADA (lower panels, n = 79) when measured in the Bristol and Denver laboratories using their local assays (left panels) and remeasured using the harmonized assays (right panels). Threshold for positivity in the respective assays are shown by the broken lines, and numbers represent the samples falling in each quadrant.