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Insulin signal transduction in muscle cells from lean and obese subjects. Insulin stimulated levels of IR tyrosine phosphorylation (A), IRS 312 serine phosphorylation (B), and Akt activation (phosphorylation) (C) in muscle cells from lean and severely obese women (n = 7). Data are represented as mean ± se. *, Significantly different from lean control (P < 0.05).
