Table 2.
Multivariate Analysis of ARD1A in Patients with Colon Cancer with Respect to DFS and OS
| Variable | DFS
|
OS
|
||||
|---|---|---|---|---|---|---|
| HR | 95%CI | P | HR | 95%CI | P | |
| Age, years | ||||||
| ≥50 | 1.00 | 1.00 | ||||
| <50 | 0.84 | 0.54–1.29 | 0.414 | 0.76 | 0.49–1.18 | 0.217 |
| Sex | ||||||
| Male | 1.00 | 1.00 | ||||
| Female | 1.07 | 0.75–1.52 | 0.714 | 1.10 | 0.77–1.58 | 0.598 |
| TNM stage | ||||||
| I | 1.00 | 1.00 | ||||
| II | 1.60 | 0.69–3.69 | 0.271 | 1.80 | 0.74–4.42 | 0.197 |
| III | 3.95 | 1.78–8.75 | 0.001 | 4.16 | 1.77–9.78 | 0.001 |
| IV | 13.50 | 6.00–30.39 | 0.000 | 18.42 | 7.71–43.97 | 0.000 |
| Histological type | ||||||
| Mucinous carcinoma | 1.00 | 1.00 | ||||
| Adenocarcinoma | 1.17 | 0.85–1.60 | 0.346 | 1.19 | 0.85–1.65 | 0.313 |
| ARD1A | ||||||
| Negative | 1.00 | 1.00 | ||||
| Positive | 1.70 | 0.96–3.00 | 0.068 | 1.91 | 1.03–3.52 | 0.039 |