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. 2010 Sep;177(3):1164–1175. doi: 10.2353/ajpath.2010.091269

Figure 2.

Figure 2

tPA promotes renal fibroblast cell DNA synthesis and BrdU incorporation. A: Representative micrographs show an increased BrdU incorporation in NRK-49F cells after incubation with 50 nmol/L tPA for 48 hours. Cells were immunostained with mouse anti-BrdU antibody (red). DAPI (blue) was used to visualize the nuclei. Arrows in the inset indicate BrdU-positive cells. B: Quantitative data show the percentages of BrdU-positive cells in control and tPA-treated groups. *P < 0.05 versus controls (n = 3).