Figure 7.

Analyses of the extent of histopathology. A: Inflammatory lesions are similar in number between wild-type, OPN^−/−, MMP-12^−/−, and OPN/MMP-12^−/− mice. B: Inflammation score is also similar across groups although there was a trend toward a lowering in the OPN/MMP-12^−/− mice. Individual values are plotted and the bar represents the mean for the group. Wild-type, N = 5; OPN^−/−, N = 5; MMP-12^−/−, N = 3; and OPN/MMP-12^−/−, N = 4. Nonparametric one-way analysis of variance with Dunn’s Multiple Comparison Test was used for statistical analysis.