Table 5.
Factors associated with abnormal ankle deep tendon reflex in patients receiving antiretroviral therapy, Mombasa, Kenya*
Predictor variable | Ankle deep tendon reflex | Univariate analysis | ||
---|---|---|---|---|
Abnormal, n = 25(25%) | Normal, n = 77(75%) | Odds ratio(95% confidence interval) | P | |
Median (quartile) years of age | 44 (36–50) | 39 (33–44) | 1.1 (1.0–1.1) | 0.04 |
Median (quartile) months receiving ART | 11.0 (7.8–18.2) | 10.2 (4.4–15.4) | 1.0 (1.0–1.1) | 0.43 |
Female | 14 (56%) | 50 (65%) | 1.5 (0.6–3.6) | 0.42 |
Median (quartile) baseline kilograms of weight | 61 (52–64) | 57 (51–62) | 1.0 (1.0–1.1) | 0.12 |
Median (quartile) baseline centimeters of height | 168.5 (161.5–172) | 161.5 (155–170) | 1.1 (1.0–1.1) | 0.06 |
Median (quartile) baseline CD4 cell count | 133 (36–188) | 146 (88–201) | 1.0 (0.99–1.0) | 0.11 |
CD4 cell count < 100 cells/mm3 | 12 (48%) | 23 (30%) | 2.2 (0.9–5.5) | 0.10 |
Clinical diagnosis of AIDS | 16 (64%) | 47 (61%) | 1.1 (0.4–2.9) | 0.79 |
Any D4T use | 23 (92%) | 73 (95%) | 0.6 (0.1–3.7) | 0.61 |
Current D4T use | 18 (72%) | 70 (91%) | 0.3 (0.08–0.8) | 0.02 |
Past D4T use | 5 (20%) | 3 (4%) | 6.2 (1.4–28.0) | 0.02 |
Current or past INH use | 4 (16%) | 14 (18%) | 0.9 (0.3–2.9) | 0.80 |
Values are no. (%) unless otherwise indicated. ART = antiretroviral therapy; AIDS = acquired immunodeficiency syndrome; D4T = stavudine; INH = isoniazid.