Table 3.

Characteristics of post-enrollment dengue cases, Nicaragua^*

Study year	Study code	Index case	Age, years	Sex	Clinical classification	IgM1	IgM2	InhE1titer	InhE2 titer	Result InhE	Primary/secondary infection	RT-PCR	Virus isolation
2006–2007	20002	276	30	F	AS	+	+	5	1,443	+	1	–	NP
	20032	2510†	13	M	AS	–	–	200	7,563	+	2	DENV-2	DENV-2
	20065	3325	24	F	AS	–	+	1,550	3,933	–	2	–	NP
	20131	3555†	40	F	AS	–	–	15	211	+	1	–	NP
2007–2008	20170	1565	14	F	AS	–	–	2,862	100,001	+	2	DENV-2	DENV-2
	20172	1565	11	F	UFI	–	+	2,011	36,547	+	2	DENV-2	DENV-2
	20213	2703	14	F	DF‡	–	+	345	100,001	+	2	DENV-2	DENV-2
	20410	2453	25	F	DF	–	+	296	16,099	+	2	DENV-2	DENV-2
	20443	1155	67	F	DF	–	+	12,724	33,942	–	2	DENV-2	–
	20497	2538	12	F	DF‡	–	+	316	18,634	+	2	DENV-2	DENV-2
	20498	2538	14	F	UFI	–	+	1,561	5,092	–	2	DENV-2	–
	20502	2538	15	M	UFI‡	–	–	4,154	20,180	+	2	DENV-2	–

^*InhE = inhibition enzyme-linked immunosorbent assay; RT-PCR = reverse transcription–polymerase chain reaction; AS = asymptomatic; NP = not processed; DENV = dengue virus; UFI = undifferentiated febrile illness; DF= dengue fever.

^†Negative index case.

^‡Febrile at enrollment.