Skip to main content
. 2010 Jul 30;22(7):2156–2170. doi: 10.1105/tpc.110.075606

Figure 7.

Figure 7.

Salient AP2 Direct Network Connections to Flowering Time and Organ Development Genes.

AP2 participates in multiple feedback loops by directly binding flowering time loci and modulating their expression in logical, reinforcing circuits. AP2 directly represses the expression of flowering promoting transcripts AP1, FUL, SEP3, and SOC1 by binding to their genomic loci. At the same time, AP2 directly promotes the expression of miR156e, which represses the floral transition by repressing the SPLs. Additional, dual feedback loops via the repressor of AP2, miR172b, are evident, with AP2 directly repressing miR172b and also reinforcing this direct action on miR172b through increased miR156 expression. Finally, AP2 directly promotes the expression of the unrelated MADS domain floral repressor, AGL15, while directly repressing the expression of AG, a key MADS domain floral identity gene.