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. Author manuscript; available in PMC: 2010 Aug 27.
Published in final edited form as: Mol Cancer Res. 2008 Jan;6(1):119–126. doi: 10.1158/1541-7786.MCR-07-0090

Table 1. Inhibition of Osx Expression Alters Tumor Phenotype.

Study Group* Blastic Lesion Incidence (%) Mixed Lesion Incidence (%) Lytic Lesion Incidence (%) Bone Lysis
Dunn 8/8 0/8 0/8 0
Dunn-si-c 6/7 1/7 0/7 0.07
Dunn-si-2 2/8 1/8 5/8 1.1†
DLM8 6/8 2/8 0/8 0.13
DLM8-si-c 8/9 0/9 1/9 0.11
DLM8-si-1 1/7 3/7 3/7 0.64‡
*

Dunn, Dunn-si-c, Dunn-si-2, DLM8, DLM8-si-c, and DLM8-si-1 cells were injected into the left tibia of nude mice. The mice (10 per group) were sacrificed 35 d after tumor cell injection. Blastic and lytic phenotypes were determined as described in Materials and Methods.

†

P < 0.01, compared with control groups.

‡

P < 0.05, compared with control groups.