Table 3.

Articular cartilage explants were cultured with IL1 (a) or NOC18 (b) for 48 hrs in 5% O₂. ATP was extracted from the explants and measured. Data shown are means with 95% confidence intervals (lower limit, upper limit), N=15.

(a)
IL1 (ng/ml)	ATP (ng/ml)
0*	68 (54, 82)
0	82 (66, 98)
0.1	72 (62, 82)
1	50 (43, 57)
10	40 (36, 45)
0 v 0.1, 1, 10	0.21, 0.0004, <0.0001
0.1 v 1, 10	0.01, 0.0004
1 v 10	0.23

(b)
NOC18 (mM)	ATP (ng/ml)
0*	54 (45, 63)
0	72 (58, 86)
0.5	69 (58, 80)
1	50 (42, 58)
2	55 (45, 65)
0 v 0.5, 1, 2	0.70, 0.01, 0.04
0.5 v 1, 2	0.02, 0.07
1 v 2	0.56

^*represents articular cartilage explants obtained from the same pigs cultured at 20% O₂. p value for 20% v 5% O₂ without IL1 = 0.11. p value for 20% v 5% O₂ without NOC18 = 0.04.