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Peak cardiac output during treadmill exercise normalized to appendicular muscle mass versus femoral blood flow during peak knee extensor exercise normalized to quadriceps muscle mass; filled triangle younger men (n = 19), open triangle older men (n = 12; a); filled circle younger women (n = 17), open circle older women (n = 17; b). From Ridout et al. (2010). Reproduced with permission from the American Physiological Society
