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Immunoblots showing the effect of 24 hours of A-779024 treatment over a broad dose range on MIA-PaCa-2 cells’ expression of several autophagy-related proteins. The relative fractions of LC3-I and LC3-II show no change with A-779024 treatment, indicating no induction of autophagy. Beclin 1 levels remained constant as well; Akt and Phospho-Akt show a slight trend toward inhibition with increasing dose of A779024. Actin is shown as a protein loading control.
