TABLE 1.
Sample Sizes and Treatment Conditions
| Strain | Control | Ethanol-Exposed | ||
|---|---|---|---|---|
| n (N) | n (N) | Reason for removal from | ||
| ethanol-exposed group (# removed)* | [Vapor] (mg/l) | |||
| 129S1/SvImJ | 8 | 15 (16) | other(1) | 6.5 |
| AKR/J | 8 | 11 (16) | BEC (3), other(2) | 6.5 |
| BALB/cByJ | 8 | 15 (16) | other(1) | 6.8 |
| BTBR T+tf/J | 8 | 14 (15) | BEC(1) | 6.9 |
| C3H/HeJ | 6 | 5 (15) | BEC(8), other(2) | 6.5 |
| C57BL/6J | 8 | 13 (16) | BEC(3) | 8.9 |
| C57BR/cdJ | 27 (28) | 48 (53) | BEC(1), other(4) | 7.7 |
| C57L/J | 5 | 9 (11) | BEC(2) | 9.3 |
| CBA/J | 8 | 16 | 6.3 | |
| CE/J | 10 (17) | 20 (36) | BEC(7), other(9) | 6.9 |
| DBA/1J | 8 | 15 | 5.8 | |
| DBA/2J | 7 | 11 (16) | BEC(5) | 6.3 |
| FVB/NJ | 6 | 14 (16) | BEC(1), other(1) | 8.0 |
| PL/J | 8 | 15 (16) | other(1) | 6.9 |
| SJL/J | 7 (8) | 11 (16) | BEC(4), other(1) | 6.9 |
|
|
||||
| Totals | 132 (141) | 232 (289) | BEC(35), other(22) | |
Control mice were injected with pyrazole and exposed only to air.
(N) signifies the original sample size at the beginning of the experiment, if different from final n. See text for explanation of differences within the Control (air) groups.
Some ethanol exposed mice were excluded from analyses for different reasons: BEC : blood ethanol concentration outside the allow able daily range (0.50 – 2.75 mg/ml) or average overall allowable daily BEC range (1.00 – 2.00 mg/ml); “other”: includes mice excluded because there were insufficient mice/strain in either the High or Low Dose group (as discussed in text), death, illness, or experimental error.
[Vapor]: average concentration of ethanol vapor over the three days.