Table 1.
Database of dose–response parameters as input in the linear-quadratic-Poisson and relative seriality models. D50 is the dose that causes 50% response probability, γ is the maximum normalized value of the dose–response gradient and s is the relative seriality, which characterizes the volume dependence of the normal tissue. The α/β ratio describes the shoulder of the cell survival curve.
| D50 (Gy) | γ | α/β | |
|---|---|---|---|
| Targets | |||
| Breast-CTV | 42.0 | 3.00 | 10.0 |
| Breast-ITV | 40.0 | 3.00 | 10.0 |
| Breast-LN | 82.0 | 2.80 | 10.0 |
| Cervix | 80.0 | 4.00 | 10.0 |
| Head and neck | 52.8 | 2.30 | 10.0 |
| Lung | 49.2 | 1.0 | 10.0 |
| Lymph nodes | 55.0 | 3.00 | 10.0 |
| Pancreas | 55.0 | 4.00 | 10.0 |
| Prostate | 80.0 | 4.00 | 10.0 |
| Seminal vesicles | 55.0 | 3.00 | 10.0 |
| Other | – | – | 10.0 |
| D50 (Gy) | γ | α/β | s | |
|---|---|---|---|---|
| Normal tissues | ||||
| Bladder | 80.0 | 4.00 | 3.0 | 0.300 |
| Cricopharyngeus | 68.4 | 6.55 | 3.0 | 0.220 |
| Esophagus | 68.0 | 2.80 | 3.0 | 3.400 |
| Heart | 70.7 | 0.96 | 3.0 | 1.000 |
| Healthy breasts | 30.0 | 5.00 | 3.0 | 0.200 |
| Healthy lungs | 30.1 | 0.97 | 3.0 | 0.010 |
| Kidney | 28.2 | 2.60 | 3.0 | 0.004 |
| Liver | 39.2 | 2.60 | 3.0 | 0.170 |
| Parotid gland | 39.0 | 0.87 | 3.0 | 1.000 |
| Rectum | 80.0 | 2.20 | 3.0 | 0.700 |
| Small bowel | 62.0 | 2.10 | 3.0 | 0.140 |
| Spinal cord | 57.0 | 6.70 | 3.0 | 1.000 |
| Stomach | 65.0 | 2.60 | 3.0 | 1.000 |
| Other | – | – | 3.0 | 1.000 |