Table 1.
Demographic and clinical characteristics of study subjects.
| KD IVIG-Responsive (n=12) |
KD IVIG-Resistant (n=8) |
Healthy Controls (n=9) |
|
|---|---|---|---|
| Age at Onset, yr | 3.29 (0.33-9) |
1.85 (0.33-4.92) |
1.65 (0.39-4.47) |
| Male, n (%) | 5 (42) | 5 (63) | 3 (33) |
| Illness Day at sample collection |
6 (4-10) |
5 (4-7) |
NA |
| Ethnicity/Race, n (% of total) |
|||
| Asian | 1 (8.3) | 0 | 0 |
| Caucasian | 4 (33) | 2 (25) | 3 (33) |
| Hispanic | 3 (25) | 4 (50) | 3 (33) |
| Mixed | 4 (33) | 2 (25) | 3 (33) |
| Coronary Artery | 8 Normal | 3 Normal | NA |
| Statusa | 4 Dilated | 3 Dilated 2 Aneurysms |
|
| White blood cells × 103/mm3 |
13.3 (5.9-23) |
13.0 (7.6-19.2) |
NA |
| Neutrophils, % | 57 (22-76) |
54 (28-73) |
NA |
| Bands, % | 8 (0-28) |
17 (0-50) |
NA |
| Absolute | 8303 | 9888 | NA |
| Neutrophil Count | (4818-16269) | (4302-14976) | |
| Lymphocytes, % | 17 (5-70) |
18 (2-34) |
NA |
| Monocytes, % | 4.5 (0-17) |
5 (2-10) |
NA |
| zHemoglobinb | −0.73 (−4.33-1) |
−1.40 (−5.83-0) |
NA |
| Erythrocyte | 59.5 | 63.5 | NA |
| Sedimentation | (27-140) | (40-140) | |
| Rate, mm/h | |||
| C Reactive | 5.5 | 18 | NA |
| Protein, mg/dL | (0.3-18.4) | (5.1-44.2) | |
| Platelets × 103/mm3 |
404 (89-541) |
394 (85-516) |
NA |
| Alanine | 69 | 12.5 | NA |
| Aminotransferase, U/L | (6-725) | (24-161) | |
| Gamma Glutamyl | 64 | 109.5 | NA |
| Transferase, U/L | (9-220) | (6-216) | |
All data presented as median (range).
a
Only significant difference between IVIG-responsive and –resistant KD subjects, p=0.04 chi square test
b
zHemoglobin, standard deviation units from the mean based on age-adjusted normal values [44] NA= not available