Table 1. Effects of acute alcohol exposure (Alcohol) on CLP induced organ injury and inflammatory responses in rats.
Sham | Alcohol | CLP | Alcohol+CLP | |
---|---|---|---|---|
Lactate (mg/dL) | 9.9±1.31 | 10.8±0.89 | 22.0±2.26*# | 23.3±1.47*# |
TNF-α (pg/ml) | 5.6±0.23 | 5.0±1.27 | 13.7±2.46*# | 17.7±1.91*# |
IL-6 (pg/ml) | 49.6±3.43 | 47.9±0.96 | 201.8±45.04*# | 242.6±59.81*# |
Pulmonary MPO (U/g) | 33.6±5.38 | 98.5±9.70* | 136.9±5.41*# | 142.3±6.18*# |
Data are expressed as means ± SE (n=5-6/group) and compared by one-way ANOVA and Student-Newman-Keuls method:
P<0.05 versus sham-operated animals;
P<0.05 versus Alcohol alone animals.