Table (3).

Associations between HCV high viral load* and participants' laboratory results stratified by their HIV status and treatment

	Overall (N=1,266)	HIV negative (N=795)	HIV-positive (N=471)
OR (95% CI) ‡
Anemia
None	Ref	Ref	Ref
Mild	0.9 (0.6-1.3)	0.7 (0.5-1.1)	1.1 (0.7-1.9)
Moderate/Severe	0.5 (0.2-1.2)	0.7 (0.2-2.2)	0.8 (0.3-2.4)
Platelet counts (cells/μL)
≥150,000	Ref	Ref	Ref
<150,000	1.0 (0.7-1.3)	0.9 (0.6-1.3)	0.9 (0.6-1.4)
Lymphocyte count (cells/μL)
≥1,500	Ref	Ref	Ref
<1,500	1.2 (1.0-1.6)	1.1 (0.7-1.5)	1.4 (0.9-2.1)
Neutrophil count (cells/μL)
<3000	Ref	Ref	Ref
≥3000	1.1 (0.8-1.4)	1.1 (0.8-1.5)	1.5 (1.0-2.4)
Serum albumin (g/dl)
<3.8	Ref	Ref	Ref
≥3.8	0.9 (0.6-1.3)	1.2 (0.7-1.9)	0.7 (0.4-1.3)
Alanine aminotrasferase (ALT)
Normal	Ref	Ref	Ref
<3 fold elevation	1.0 (0.7-1.3)	1.2 (0.8-1.8)	0.6 (0.3-1.0)
≥3 fold elevation	0.9 (0.6-1.3)	1.0 (0.6-1.6)	0.6 (0.3-1.1)
Aspartate aminotransferase (AST)
Normal	Ref	Ref	Ref
<3 fold elevation	1.2 (0.9-1.5)	1.3 (0.9-1.8)	0.6 (0.3-1.1)
≥3 fold elevation	1.0 (0.7-1.5)	0.8 (0.5-1.4)	0.7 (0.3-1.4)
AST/ALT ratio
<1	Ref	Ref	Ref
1-<1.2	1.3 (0.9-2.0)	1.0 (0.6-1.8)	1.6 (0.9-2.9)
≥1.2	0.9 (0.6-1.2)	0.6 (0.4-0.9)	1.2 (0.7-1.9)
APRI (AST/platelet)
<0.4	Ref	Ref	Ref
0.4-1.49	1.2 (0.9-1.7)	1.3 (0.9-1.9)	0.6 (0.3-1.3)
≥1.5	1.0 (0.7-1.5)	0.9 (0.5-1.5)	0.6 (0.2-1.2)
Total bilirubin (mg/dl)
≤1	Ref	Ref	Ref
>1	1.2 (0.9-1.7)	1.0 (0.6-1.6)	1.3 (0.8-2.2)
Detectable HIV-1 viremia
No		N/A	Ref
Yes			1.1 (0.8-1.7)
CD4 count (cells/μL)
>500		N/A	Ref
200-500			1.3 (0.8-2.5)
<200			1.4 (0.7-2.5)

^‡Odds ratios (OR) and 95% confidence intervals (CI) comparing subjects with high HCV viral load to those with low viral load

Underlined OR are significant at p<0.05