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. Author manuscript; available in PMC: 2011 Jul 1.
Published in final edited form as: Trop Med Int Health. 2010 May 14;15(7):833–841. doi: 10.1111/j.1365-3156.2010.02539.x

Table 3.

Predictors of HIV-exposed and HIV-infected children becoming lost to follow-up: Unadjustedμ and Adjusted Hazard Ratios (HR) and 95% Confidence Intervals (CI)

HIV Exposed HIV Infected
Unadjusted HR
(95% CI)		 Adjusted HRμ
(95% CI)		 Unadjusted HR
(95% CI)		 Adjusted HR
(95% CI)
Gender (male vs. female) 1.00(0.89-1.12) - 1.10 (0.95-1.26) -
Age per year increase* 0.87 (0.85-0.89)
% missing: 0%		 0.90 (0.85-0.96) 0.96 (0.94-0.99)
% missing: 0%		 0.93 (0.86-1.00)
Orphaned at enrolment
(yes vs. no) 		0.31 (0.26-0.37) 1.57 (1.23-1.64) 0.83(0.70-0.98) 1.09 (0.75-1.60)
Attending urban clinic
(yes vs. no)* 		1.24(1.11-1.39) 0.93(0.83-1.04) 1.06 (0.92-1.22) -
Severely low weight for
height (z ≤−3 vs.>-3)* 		2.10 (1.68-2.61)
% missing:0%		 1.69 (1.25-2.28) 3.82(2.74-5.32)
% missing: 25%		 1.61(0.66-3.93)
Severely immune-
suppressed (per age cate-
gory)* 		1.35(1.04-1.76)

% missing: 86%		 - 1.83(1.46-2.30)

% missing: 32%		 2.17 (1.51-3.12)
CDC clinical stage(B/C vs.
A) 		0.59 (0.56-0.70)
% missing: 0%		 1.41(1.14-1.74) 1.21 (1.02-1.43)
% missing: 30%		 0.85 (0.59-1.23)
Enrolled 2005-2006
(vs. <2005) 		0.62(0.56-0.69) 0.68(0.58-0.80) 0.85(0.68-1.06) 0.80(0.43-1.48)
Enrolled≥2007
(vs. <2005) 		0.62 (0.55-0.70) 0.71(0.60-0.85) 0.70(0.55-0.91) 0.92 (0.47-1.84)
Received food supplemen-
tation(yes vs. no)* 		0.52(0.37-0.72) 0.58(0.32-1.04) 0.09 (0.02-0.38) -
Became HIV-infected
(yes vs. no)* 		0.22(0.19-0.25) 0.26(0.21-0.32) - -
Receiving antiretrovirals
(yes vs. no)* 		0.47(0.41-0.55)
% missing: 0%		 1.56 (1.23-1.99) 0.94 (0.81-1.08)
% missing: 0%		 -
μ

Completeness of data for cross-sectional variables are presented in Table 1. Completeness of data for longitudinal variables (age, weight for height, immune suppression, clinical stage) are presented as a proportion of the expected frequency of measures as per clinical algorithms for HIV-exposed and HIV-infected children, respectively,pre-imputation.

*

Longitudinal variables from enrolment until last visit using all available data.

Ω

The variables used in the full model are those that were significant in the univariable models(p<0.05). Some univariately significant variables are not included in the multi-variable models because the missing-data lead to non-estimable regression co-efficients.i.