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. Author manuscript; available in PMC: 2011 May 1.
Published in final edited form as: Expert Rev Mol Diagn. 2010 Jul;10(5):651–665. doi: 10.1586/erm.10.45

Figure 3. Suggested algorithm for molecular and genetic testing for Lynch syndrome.

Figure 3

For purposes of feasibility, IHC alone is a reasonable strategy.

For inconclusive results, an intensive cancer screening may still be recommended.

CRC: Colorectal cancer; IHC: Immunohistochemistry; LS: Lynch syndrome; MMR: Mismatch repair; MSI: Microsatellite instability; MSS: Microsatellite stable.