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Gene-specific cancer risks.
| Mismatch repair gene | Cumulative risk of CRC by age 70 years (%) | Cumulative risk of EC by age 70 years (%) |
|---|---|---|
| MLH1 | ||
| • Males | ~70 | |
| • Females | ~50 | ~30 |
| MSH2 | ||
| • Males | ~50 | |
| • Females | ~40 | ~45 |
| MSH6 | ||
| • Males | 22 | |
| • Females | 10 | 26 |
| PMS2 | ||
| • Males | 20 | |
| • Females | 15 | 15 |
