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. Author manuscript; available in PMC: 2010 Aug 28.
Published in final edited form as: Nat Struct Mol Biol. 2008 Aug;15(8):777–779. doi: 10.1038/nsmb0808-777

Figure 1.

Figure 1

Structural elements of yeast pol II critical for α-amanitin action. From the structure of the yeast pol II elongation complex bound to α-amanitin (2VUM)3: located within mobile Trigger Loop (cartoon, blue) are His1085 (sticks, pink) making H-bonds with α-amanitin (sticks, yellow)2,3, and Leu1081 (sticks, orange) “wedging” into Bridge Helix (cartoon, green)3.