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. Author manuscript; available in PMC: 2011 Jan 6.
Published in final edited form as: Immunol Cell Biol. 2010 Apr 27;89(1):122–129. doi: 10.1038/icb.2010.61

FIGURE 4. pD2 induces a short-lived activation signal in a pD1-3/4 cross-reactive cell line.

FIGURE 4

(A) Time course of pERK1/2 after pD2 stimulation of the cell line 10C11. One of 2 independent experiments is shown. (B) Phosphorylation of CD3ζ after stimulation of 10C11 with each of the three peptide variants. Histograms are shaded to emphasize the change in MFI. One of 3 independent experiments is shown. (C) Time course of CD137 expression after stimulation of 10C11 with pD1, pD2, and a control non-dengue HLA-A*1101-restricted viral peptide. The peptide concentration used for these experiments was 10μg/mL. NS = no stimulation.