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. Author manuscript; available in PMC: 2011 Oct 31.
Published in final edited form as: Respir Physiol Neurobiol. 2010 May 8;173(3):264–273. doi: 10.1016/j.resp.2010.04.024

Figure 4.

Figure 4

Intrinsic chemosensitive response to hypercapnic acidosis in LC neurons from the neonatal rat brainstem. Both high Mg2+/low Ca2+ and carbenoxolone were used to prevent synaptic communication between neurons. CS responses divided into two age classes: post-natal days P0-9 and P10-19, referenced as <P10 and >P10, respectively. N=23 for <P10, N=24 for >P10. A. Percent of neurons activated (increased firing rate) by HA (15% CO2). B. Chemosensitive index (relative magnitude of the chemosensitive response) for those neurons activated by HA. N=16 for <P10, N=5 for >P10. The height of the bars represents the means and the error bars represent one SEM.