Table 2.
Overall association between dietary proteins, calcium (density of nutrients in g or mg/1000 kcal), and RNAE and fracture risk (separate Cox models for each nutritional
| Variables | Model | Quartile 1 | Quartile 2 | Quartile 3 | Quartile 4 |
|---|---|---|---|---|---|
| Total proteins (g/1000 kcal) | Cut-off | < 40.75 | 40.75 – 45.16 | 45.16 – 50.11 | > 50.11 |
| Age-adjusted RR | 1 | 1.05 (0.94–1.18) | 1.00 (0.89–1.12) | 1.10 (0.98–1.23) | |
| Multivariate RR | 1 | 1.05 (0.93–1.17) | 0.99 (0.88–1.11) | 1.06 (0.94–1.19) | |
| Animal proteins (g/1000 kcal) | Cut-off | < 22.42 | 22.42 – 27.75 | 27.75 – 33.52 | > 33.52 |
| Age-adjusted RR | 1 | 1.07 (0.96–1.20) | 1.05 (0.94–1.18) | 1.14 (1.02–1.27) | |
| Multivariate RR | 1 | 1.07 (0.95–1.20) | 1.04 (0.93–1.16) | 1.10 (0.98–1.24) | |
| Vegetable proteins (g/1000 kcal) | Cut-off | < 10.07 | 10.07 – 12.01 | 12.01 – 14.12 | > 14.12 |
| Age-adjusted RR | 0.94 (0.84–1.06) | 0.95 (0.85–1.06) | 0.94 (0.84–1.05) | ||
| Multivariate RR | 1 | 0.95 (0.85–1.06) | 0.96 (0.85–1.07) | 0.95 (0.85–1.06) | |
| Total proteins by weight (g/kg) | Cut-off | < 1.15 | 1.15–1.41 | 1.41–1.71 | >1.71 |
| Age-adjusted RR | 1 | 0.96 (0.86–1.07) | 0.97 (0.87–1.08) | 0.92 (0.82–1.03) | |
| Multivariate RR | 1 | 1.00 (0.88–1.12) | 1.03 (0.90–1.18) | 1.02 (0.86–1.20) | |
| RNAE (mEq) | Cut-off | < 34.2 | 34.2 – 45.7 | 45.7 – 57.1 | > 57.1 |
| Age-adjusted RR | 1 | 1.06 (0.95–1.19) | 1.10 (0.98–1.23) | 1.03 (0.92–1.15) | |
| Multivariate RR | 1 | 1.06 (0.95–1.19) | 1.11 (0.99–1.24) | 1.05 (0.93–1.19) | |
| Variables | Quartile 1 | Quartile 2 | Quartile 3 | Quartile 4 | Supplement use | |
|---|---|---|---|---|---|---|
| Calcium (mg/1000kcal) | Cut-off | < 417.3 | 417.3 – 500.6 | 500.6 – 604.3 | > 604.3 | |
| Age-adjusted RR | 1 | 1.06 (0.94–1.19) | 1.01 (0.90–1.14) | 0.92 (0.82–1.04) | 0.85 (0.73–0.98) | |
| Multivariate RR | 1 | 1.05 (0.94–1.19) | 1.00 (0.89–1.13) | 0.91 (0.80–1.03) | 0.83 (0.72–0.96) | |