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. Author manuscript; available in PMC: 2010 Aug 30.
Published in final edited form as: J Nucl Med. 2010 Jan 15;51(2):210–218. doi: 10.2967/jnumed.109.063701

FIGURE 2.

FIGURE 2

Head movement can cause transmission-emission (TX-EM) misalignment during a dynamic brain PET. (A) An early non-AC EM frame is shown to be fused well with the TX image taken at the start of the study. Both images are shown at the same transaxial plane. (B) A late non-AC EM frame is now fused with the original TX image at the same transaxial plane from before. Since the subject’s head moves away from the PET gantry after the acquisition of the early non-AC EM frame, the mismatched TX-EM would cause an incorrect ACF matrix to be applied to the late non-AC EM frame. (C) After applying the first part of the MC method, the original TX image is matched to the late EM image. This produces an accurate ACF matrix that can be used to properly reconstruct the late EM frame.