Table 1.
Characteristics of the study population. Groups based on eGFR or being on hemodialysis.
| GFR | ESRD on | |||
|---|---|---|---|---|
| ≥60 mL/min | <60 mL/min | hemodialysis | ||
| (n = 257) | (n = 162) | (n = 22) | t-test or χ 2 | |
| Characteristics | Mean ± SE or % (n) | P | ||
| Age (yr) | 62.6 ± 0.8 | 73.7 ± 0.7 | 65.0 ± 2.9 | <.0005 |
| Male Gender | 78.6 (202) | 75.9 (123) | 68.2 (15) | NS |
| Caucasian Race | 72.0 (185) | 82.7 (134) | 72.7 (16) | .041 |
| Hypertension | 70.8 (182) | 70.8 (114) | 90.9 (20) | NS |
| Diabetes Mellitus | 28.8 (74) | 27.2 (44) | 54.5 (12) | .028 |
| Ischemic Heart Disease | 77.0 (151) | 83.2 (109) | 88.9 (16) | NS |
| Ejection Fraction (%) | 26.6 ± 0.8 | 25.2 ± 0.8 | 25.0 ± 2.6 | NS |
| eGFR (mL/min) | 93.6 ± 2.0 | 44.7 ± 0.8 | 10.3 ± 0.4 | <.0005 |
| Creatinine (mg/dl) | 1.02 ± 0.02 | 1.52 ± 0.04 | 7.14 ± 0.30 | <.0005 |
| Magnesium (mg/dl) | 1.75 ± 0.02 | 1.77 ± 0.02 | 2.01 ± 0.5 | <.0005 |
| Potasium (mEq/L) | 4.16 ± 0.03 | 4.28 ± 0.43 | 4.68 ± 0.14 | <.0005 |
| Amiodarone | 15.6 (40) | 18.5 (30) | 40.9 (9) | .012 |
| Atrial fibrillation | 19.8 (51) | 28.4 (46) | 36.4 (8) | .049 |
| DFT > 20 Joules | 35.3 (88) | 27.7 (43) | 66.7 (2) | .129 |
| Beta-blockers | 46.7 (120) | 40.7 (66) | 63.6 (14) | .103 |
| ACEIs/ARBs | 78.6 (202) | 69.1 (112) | 59.1 (13) | .025 |
| Reason for ICD | NS | |||
| Primary prevention | 51.3 (132) | 56.7 (92) | 54.5 (12) | |
| Secondary prevention | 48.8 (125) | 43.5 (70) | 45.4 (10) | |
| Type of ICD | .112 | |||
| Single Chamber | 30.0 (77) | 39.5 (64) | 36.4 (8) | |
| Dual Chamber | 59.1 (152) | 45.7 (74) | 54.5 (12) | |
| Biventricular | 10.9 (28) | 14.8 (24) | 9.1 (2) | |
NS: P > .05.