Table 1.
Parameters used in the simulations. Values that are different from “Normal neurulation” are shown in boldface. The L force values are those acting along the midsagittal plane of the embryo and the pair of values shown in Case S3 correspond to the sides labeled A (active) and I (inactive).
| Tissue and properties | Case | |||||||
|---|---|---|---|---|---|---|---|---|
| S1 Normal neurulation | S2 Reduced L force | S3 Unilateral L | S4 No L forces | S5 No ridge forces | S6 Increased NNE tension | S7 Increased thickness | ||
| All tissues | Thickness | 50 | 50 | 50 | 50 | 50 | 50 | 100 |
| Neural plate | γapical (nN) | 61 | 61 | 61 | 61 | 61 | 61 | 61 |
| γbasal (nN) | 9.1 | 9.1 | 9.1 | 9.1 | 9.1 | 9.1 | 9.1 | |
| L(nN∕μm) | 20 | 16 | 20(A), 0(I) | 0 | 20 | 20 | 20 | |
| Neural ridges | γapical (nN) | 9.1 | 9.1 | 9.1 | 9.1 | 0 | 9.1 | 9.1 |
| γbasal (nN) | 9.1 | 9.1 | 9.1 | 9.1 | 0 | 9.1 | 9.1 | |
| NNE | γapical (nN) | 9.1 | 9.1 | 9.1 | 9.1 | 9.1 | 18.3 | 9.1 |
| γbasal (nN) | 9.1 | 9.1 | 9.1 | 9.1 | 9.1 | 18.3 | 9.1 | |