Fatty acid metabolism measurements obtained in ZDF and lean rats by compartmental modeling of 11C-palmitate PET data. MFAUP = myocardial fatty acid uptake; MFAU = myocardial fatty acid utilization; MFAO = myocardial fatty acid oxidation; MFAO/MFAU myocardial FFA that was oxidized. *P < 0.001; **P < 0.01 Reproduced with permission from Welch MJ, Lewis JS, Kim J, Sharp TL, Dence CS, Gropler RJ, Herrero P. Assessment of myocardial metabolism in diabetic rats using small-animal PET: a feasibility study. J Nucl Med. Apr 2006;47(4):689–697.