Table 2.

VEGF retention time in the lung¹

VEGF Delivery form	Decay constant2	Half-life3 (hr)	Mean lifetime3 (hr)	90% lifetime3 (hr)
Free	0.1724	4	6	13
DS-CS PECs	0.0216	32	46	106

¹Calculated from equations derived from Figure 9.

²In the exponential decay equation, dC/dt = −λC, λ is referred to as decay constant. Integration of this equation gives lnC_t = −λt + a, or C_t = e^−λte^a. At time 0, C₀ = e^a. Thus, C_t = C₀e^−λt. Comparing this equation with those in Figure 9, the decay constants were obtained.

³The half-life, mean lifetime, and 90% lifetime were calculated as C_t/C₀ = 0.5/1, C_t/C₀ = 0.368/1, and C_t/C₀ = 0.1/1, respectively.