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. 2010 Aug 2;120(9):3296–3309. doi: 10.1172/JCI41490

Figure 6. RbΔfl mammary tumors cluster with DMBA and Tag-induced basal-like or T121-induced luminal-B–like breast tumors.

Figure 6

(A) Overview of expression of 866 reference genes in tumors from RbΔfl and 13 mouse models of breast cancer. Colored regions at left correspond to the regions shown in B–F. (B) Selected genes representing the luminal gene cluster. (C) CK5 basal-like gene cluster. (D) CK14 basal-like gene cluster. (E) Proliferation-associated gene cluster. (F) EMT gene cluster. (G) Subset of proliferation-associated genes. Asterisks at the top mark the 9 RbΔfl tumors; tumor models that clustered with RbΔfl tumors are highlighted at the bottom. DMBA, 7,12-dimethylbenz[a]-anthracene.