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. 2010 Aug 2;120(9):3296–3309. doi: 10.1172/JCI41490

Figure 9. Identification of p53 mutations in Tag/basal-like and EMT RbΔfl tumors.

Figure 9

(A) DNA sequencing reaction around K129 in control DNA (left) and tumor 3 (right). (B) Schematic representation of human p53 and relative location (asterisks) of mutations identified in mouse RbΔfl tumors: Tag/basal-like tumor 3, K129M (human, K132M); Tag/basal-like tumor 4, H165R (human, H168R); EMT tumors 18 and 30, C138R (human, C141R). TAD, N-terminal transactivation domain; PRR, proline-rich region; TET, tetramerization domain, CT, C terminus.