Table 1. This table shows 21 KEGG pathways that were found to be significantly perturbed by nephrotoxic chemicals (FDR1%).
KEGG ID | Pathway Name | Size | Score |
rno05020 | Parkinson's disease | 10 | 31.71 |
rno00564 | Glycerophospholipid metabolism | 25 | 31.29 |
rno05215 | Prostate cancer | 52 | 26.66 |
rno02010 | ABC transporters - General | 13 | 26.35 |
rno04070 | Phosphatidylinositol signaling system | 32 | 22.56 |
rno04130 | SNARE interactions in vesicular transport | 24 | 21.54 |
rno00760 | Nicotinate and nicotinamide metabolism | 10 | 21.17 |
rno01430 | Cell Communication | 45 | 21.07 |
rno00530 | Aminosugars metabolism | 9 | 20.77 |
rno04120 | Ubiquitin mediated proteolysis | 65 | 20.40 |
rno05030 | Amyotrophic lateral sclerosis (ALS) | 16 | 19.64 |
rno03010 | Ribosome | 26 | 19.54 |
rno03050 | Proteasome | 20 | 19.35 |
rno05212 | Pancreatic cancer | 50 | 19.21 |
rno00230 | Purine metabolism | 64 | 16.14 |
rno04330 | Notch signaling pathway | 20 | 15.31 |
rno01031 | Glycan structures - biosynthesis 2 | 17 | 14.96 |
rno04612 | Antigen processing and presentation | 23 | 14.96 |
rno04510 | Focal adhesion | 102 | 14.49 |
rno04320 | Dorso-ventral axis formation | 17 | 14.32 |
rno05211 | Renal cell carcinoma | 52 | 13.71 |
The number of genes in each pathway and the value of the hotelling statistics are shown respectively in the third and fourth columns size column.