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Inhibition of virus entry by Rab5 and Rab7 dominant-negative mutants. (A) 293T/CD20 cells transiently transfected with wild-type or dominant-negative mutant Rab5 were spin-infected with various lentiviruses (FUGW/αCD20+SINmu, FUGW/αCd20+HAmu, FUGW/VSVG, or MIG/VSVG). (B) 293T/CD20 cells transiently transfected with wild-type or dominant-negative mutant Rab7 were spin-infected with different viruses as indicated above. The percentage of GFP+ cells was analyzed by FACS.
