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. Author manuscript; available in PMC: 2012 Feb 1.
Published in final edited form as: Neurobiol Aging. 2009 Mar 27;32(2):249–256. doi: 10.1016/j.neurobiolaging.2009.02.014

Figure 1.

Figure 1

Locations and linkage disequilibrium (LD) map structure of single nucleotide polymorphisms (SNPs) in the TTR gene region. The LD maps for the African American (AA) and Caucasian family samples are shown above and below the gene structure diagram, respectively. Measures of LD among all possible pairs of SNPs (identified by number using the scheme in Table 1) are shown graphically according to the shade of red where white represents very low D’ and dark red represents very high D’ and numerically denoted by the r2 values within each square. Indeterminate estimates of LD are denoted by blue shading. The TTR gene structure including intergenic regions (white), introns (green) and exons (purple) is shown starting from the 5’ upstream region on the left.