Table 3.

Number of Adverse Events Reported by Grade

Adverse Event	Grade 1	Grade 2	Grade 3	Grade 4
Hyperlipidemia	1
Nausea	7	2
Vomiting	3	1
Constipation	5	1
Fatigue	7	8
Shortness of breath	1
Rash	3
Diarrhea	4
Neutropenia	2
Hyperglycemia	1
Leukopenia	3	1
AST	4	2
ALT	3	1
Thrombocytopenia	7	10	1	1
UTI	1
Anorexia	1	2
Neuropathy	2
Abdominal pain	2	1
Hypercalcemia	1
Hyperbilirubinemia	1	1
Myalgia	1
Drop in hemoglobin	5
Lymphopenia	1
Hypertension	2	1
Hypokalemia				1
Cold sensitivity	1
Mucositis	1

Abbreviations: ALT = alanine aminotransferase; AST = aspartate aminotransferase; UTI = urinary tract infection