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. Author manuscript; available in PMC: 2011 Nov 1.
Published in final edited form as: J Cell Physiol. 2010 Nov;225(2):406–416. doi: 10.1002/jcp.22289

Figure 4. Regulation of LPS-induced ptgs2 mRNA by β-arrestins in vivo.

Figure 4

Wild type, β-arrestin-1 and −2 KO mice were injected with LPS as described in Fig 2. Spleens were collected at the indicated time points after LPS-injection or from untreated mice (indicated as 0 time point). Messenger RNA levels for ptgs2 was determined by real-time Q-RT-PCR. N=3 mice per genotype for each time point. Data were analyzed by two-way ANOVA with Bonferroni post-test. *p<0.05 compared between β-arrestin-1 or −2 and wild type mice at the respective time points.