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. Author manuscript; available in PMC: 2011 Nov 1.
Published in final edited form as: J Cell Physiol. 2010 Nov;225(2):406–416. doi: 10.1002/jcp.22289

Figure 5. Regulation of IL-1β (A), IL-12 (B&C) and IFNγ (D) production by β-arrestins in CD11b+ splenocytes.

Figure 5

CD11b+ splenocytes were obtained as described in the methods. Cells were treated or not with LPS (5 μg/ml) for the indicated time points, supernatants collected and cytokine levels determined by ELISA. The levels (in pg) were then normalized to μg of total cellular protein. N=5 mice per genotype. Data were analyzed by two-way ANOVA with Bonferroni post-test. #p<0.05, ##p<0.01, ###p<0.001 compared between β-arrestin-2 KO and wild type mice.